GHK-Cu
Copper tripeptide, collagen signalling for skinA copper peptide protocol for skin quality and collagen signalling, matched to your skin’s biology, tracked photographically.
Plasma GHK falls by roughly 60% between age 20 and 60, the decline tracks visibly with skin ageing. Restoring it supports collagen signalling and repair; your consultant will be direct about what is and isn’t established. Full reference →
Who this is for
Adults with skin-quality, texture, or ageing concerns, where peptide therapy will genuinely help. Candidacy is decided against your skin history and photographs, never by a checkout flow.
How the program works
Your consultant goes through your goals, history, and whether this therapy is appropriate. If it isn't, you'll hear that instead.
Baseline photography and skin assessment. Your protocol ships once your program is agreed.
Topical daily, injectable where the protocol includes it. Photo review at week 6, messaging in between.
Photographs compared against baseline. Together you decide: continue, adjust, or maintain with topicals alone.
Common questions
Texture and hydration often shift within weeks; firmness is slower, because collagen remodelling runs on months. Progress is compared photographically at weeks 6 and 12 rather than promised.
Most protocols start topical. Micro-injections are added only where the indication supports it: deeper texture work, scarring, or post-procedure repair.
Your program is quoted in full after your consultation, before anything is supplied. There is no set program price because there is no off-the-shelf product: formulation, strength and duration differ per patient.
GHK-Cu stands for glycyl-L-histidyl-L-lysine copper complex. "GHK" is the single-letter amino acid code for the tripeptide glycine-histidine-lysine, and "Cu" is the chemical symbol for copper. The compound is also referenced as copper tripeptide-1, copper peptide GHK, or simply GHK copper. All four terms describe the same molecule.
Yes. GHK-Cu, GHKCu, and GHK Cu are three spellings of the same compound. The hyphenated form appears in peer-reviewed literature, the unspaced form is common in product listings, and the space-separated form is used by writers who treat Cu as a separate elemental symbol. Chemistry, source, and research applications are identical.
GHK-Cu is one specific copper-binding tripeptide. "Copper peptides" is a broader umbrella covering any peptide sequence that binds copper, including short oligopeptides used in cosmetic chemistry. GHK-Cu is the most extensively studied member of that family and serves as the literature benchmark against which newer copper peptides are characterised.
The GHK-Cu 50 Pen is pre-filled and ready to use. A research handler attaches a fresh sterile single-use needle, primes the pen to clear air following the supplied instructions, dials the required dose on the selector (1mg, 2mg, or 3mg), administers subcutaneously, and disposes of the needle. There is no mixing or preparation step. Only ever considered after a consultation.
A tripeptide that carries copper
GHK binds Cu(II) with high affinity (logK around 16.4) and shuttles the bound copper across cellular membranes. In vitro studies have used this transport activity to deliver copper to fibroblast and keratinocyte cultures where copper-dependent enzymes can act on it.
A review by Pickart and Margolina (Int J Mol Sci, 2018;19(7):1987) summarises bioinformatic analyses reporting that GHK and the copper complex modulate expression of several thousand human genes across pathways relevant to wound repair, DNA repair, and antioxidant defence.
Published in vitro studies have documented effects on fibroblast collagen synthesis, glycosaminoglycan production, and matrix metalloproteinase activity. Researchers use GHK-Cu as a tool for probing extracellular matrix biology in three-dimensional culture models.
In vitro studies have observed copper-dependent superoxide dismutase activity in GHK-Cu-treated cell cultures. The copper binding geometry is thought to mimic the active site of native SOD enzymes, providing a useful research tool for oxidative stress models.
GHK Cu is also searched as GHK copper, Copper tripeptide-1, GHKCu.